Produce cryo-lamellas for cryo-tomography using autoloader TEM systems.Cryo-dedicated hardware inside the DualBeam system chamber ensures optimal sample preparation while maintaining cryo conditions. Cryo specimens are mounted in dedicated Cryo-FIB AutoGrids which can be loaded into AutoLoader TEM systems.
Create thinner cryo-lamella without cutting artifacts. Ion beam milling enables creation of compression-free cryo-lamella samples for TEM tomography imaging. This method avoids artifacts such as mechanical compression inevitable for mechanical cryo-sectioning approaches using cryo-ultramicrotomes.
Improve sample preparation precision. Guided user software and Thermo Scientific™ MAPS™ correlation software makes the Aquilos Cryo-FIB easy to use, even for inexperienced users.
In press. Science, 2017. DOI: 10.1126/science.aal2130
Courtesy: Joe Pogliano and Elizabeth Villa, 2017