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Vitrobot™ Mark IV - Automated sample vitrification for the Cryo-TEM workflow

Vitrobot™ Mark IV, a fully automated vitrification device

As a part of the first step in the FEI Cryo-TEM workflow, researchers can create high quality vitrified samples for single particle analysis or cryo-tomography research applications. Vitrobot offers fully automated vitrification, fast and easy. It performs the cryo-fixation process at constant physical and mechanical conditions like temperature, relative humidity, blotting conditions and freezing velocity. This ensures high quality cryo-fixation results and a high sample preparation throughput prior to cryo-TEM observation.

The Vitrobot’s controlled-environment technology prevents cooling- and concentration artifacts that are inevitable in other freezing protocols. The transfer from the vitrification medium into the liquid nitrogen atmosphere has been automated,  ensuring consistent sample quality at high sample throughput.


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Vitrobot Benefits


  • User defined settings ensure maximum flexibility
  • Fully automated, reproducible vitrification of suspensions
  • High vitrification quality through controlled environment
  • High sample throughput
  • An effective user interface assures easy and flexible instrument control

 


 



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Technical Specifications
  Weight Dimensions (L/W/H) Power Supply
Vitrobot™ Mark IV 31 kg 413/260/890 mm Voltage: 110–230 V / 50–60 Hz
Fuse: 4 AT (110 V USA) / 2 AT (230 V Europe)
Power cable: 90–250 V
Operating parameters
  • Working temperature 4 – 60° C (at an ambient temperature range between 18 – 25° C)
  • Peltier controlled heating/cooling
  • Maintain relative humidity at 100%
  • Ultrasonic controlled humidification
Life Sciences
  • Cryo Fixation
  • Single Particle Analysis
  • Cellular Biology

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