Since its introduction in 2005, the Titan's superior product design and proven ability to deliver ground-breaking results have made it the preferred S/TEM of leading researchers around the world. The FEI Titan™ S/TEM family includes the world's most powerful, commercially-available scanning/transmission electron microscopes (s/TEM): the Titan™ 80-300, Titan3™ and Titan Krios™. Built around a revolutionary 80-300kV electron column, all Titans enable sub-Ångström, atomic scale discovery and exploration in both TEM and S/TEM modes over a wide range of materials and operating conditions. The newest member of the family, Titan Krios, extends the capabilities of the Titan3 to cellular and structural biologists, allowing them to visualize the intricate mechanisms of individual proteins and macromolecules, and localize that activity within the three dimensional architecture of the cell.
Titan Family [PDF 332KB]
Advantages and Capabilities
The Titan is the first and only S/TEM designed to fully realize the benefits of corrected S/TEM. Aberration correction breaks through the fundamental optical limitations of magnetic lenses, but requires equally fundamental changes in system design to achieve the stability required for ultra high resolution imaging and analysis. The Titan's oversize column was specifically designed for mechanical stability with the added length of probe and image correctors. Its proprietary constant power lenses and advanced power supplies provide the needed thermal and electronic stability.
The Titan Krios is the tool for obtaining fast, fully automated, high content three dimensional information about biological cells down to the scale resolving individual molecular complexes. It perfectly complements the cellular scale observations available from light microscopy and the atomic scale analysis provided by NMR and X-Ray diffraction. Advanced automation makes analysis fast and easy, increasing experimental productivity and enabling the high-volume analysis needed for complex biological systems.
The Titan3 includes a newly designed base to provide ultra stable support for a column with both image and probe correctors and a monochromator. An environmental enclosure effectively isolates the column from external interferences and at the same time relaxes facility requirements-and cost. High speed remote control removes even the operator from the instrument environment, a change that will be welcomed by most operators. A larger pole piece gap, permitted by the corrected optics, brings new flexibility to high resolution TEM applications such as tomography, cryo TEM, environmental TEM and dynamic experiments. Field upgrades that permit the addition of correctors or a monochromator to an existing column provide budgetary flexibility as well.
With its ability to deliver atomic scale imaging and analysis on a stable, easy to use platform, the Titan provides today's leading researchers with access to a whole new world of investigation where many of tomorrow's most important discoveries will surely be made.
Applications with Titan
The Titan family of microscopy tools are excellent performers for applications similar to the following: